哈尔明
外观
(重定向自骆驼蓬碱)
Harmine | |||
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IUPAC名 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole | |||
识别 | |||
CAS号 | 442-51-3 | ||
PubChem | 5280953 | ||
ChemSpider | 4444445 | ||
SMILES |
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InChI |
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InChIKey | BXNJHAXVSOCGBA-UHFFFAOYAR | ||
ChEBI | 28121 | ||
DrugBank | DB07919 | ||
KEGG | C06538 | ||
性质 | |||
化学式 | C13H12N2O | ||
摩尔质量 | 212.25 g/mol g·mol⁻¹ | ||
密度 | 1.326 g/cm3 | ||
熔点 | 321 °C(594 K) | ||
溶解性(水) | insoluble[1] | ||
溶解性(Dimethyl sulfoxide) | 100mM[1] | ||
溶解性(Ethanol) | 1 mg/mL[1] | ||
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。 |
哈尔明(英語:Harmine,也译为骆驼蓬碱)是一种β-咔啉类生物碱,化学式C13H12N2O。它存在于很多植物中,如骆驼蓬和卡披木。[2]它可以可逆地抑制单胺氧化酶A(MAO-A),但不抑制MAO-B。[3]
参考文献
[编辑]- ^ 1.0 1.1 1.2 Harmine - CAS 442-51-3. scbio.de. Santa Cruz Biotechnology, Inc. [27 October 2015]. (原始内容存档于2015-09-24).
- ^ Djamshidian A, et al. Banisteriopsis caapi, a Forgotten Potential Therapy for Parkinson's Disease?. Movement Disorders Clinical Practice. 2015, 3 (1): 19–26. PMC 6353393 . PMID 30713897. doi:10.1002/mdc3.12242.
- ^ Frecska E, Bokor P, Winkelman M. The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization. Frontiers in Pharmacology. 2016, 7: 35. PMC 4773875 . PMID 26973523. doi:10.3389/fphar.2016.00035 .